Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489677 | 1.00 | JAK2 (0.34) | JAK2BTKIDO1TDO2 | |
| SCHEMBL31489613 | 0.91 | JAK2 (0.34) | JAK2BTKIDO1TDO2 | |
| SCHEMBL31489811 | 0.88 | — | — | |
| SCHEMBL31489563 | 0.84 | EGFR (0.32) | — | |
| SCHEMBL31489632 | 0.77 | IRAK4 (0.35) | IDO1TDO2 | |
| SCHEMBL31489290 | 0.76 | LPL (0.34) | JAK2BTKIDO1TDO2 | |
| SCHEMBL31489425 | 0.76 | JAK2 (0.31) | JAK2BTK | |
| SCHEMBL31489436 | 0.76 | JAK2 (0.33) | JAK2BTK | |
| SCHEMBL31489137 | 0.74 | KDM4E (0.30) | — | |
| SCHEMBL31489862 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |