Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489570 | 0.81 | MKNK1 (0.40) | JAK2JAK1TYK2JAK3GPR55 | |
| SCHEMBL31489665 | 0.81 | CYP11B2 (0.38) | — | |
| SCHEMBL31489816 | 0.73 | CYP11B2 (0.40) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489637 | 0.73 | MKNK1 (0.39) | JAK2JAK1TYK2JAK3GPR55 | |
| SCHEMBL31489553 | 0.73 | CYP11B2 (0.40) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489407 | 0.72 | CHEK1 (0.31) | — | |
| SCHEMBL31489450 | 0.72 | CHEK1 (0.31) | — | |
| SCHEMBL31489373 | 0.70 | MKNK1 (0.38) | JAK2JAK1TYK2JAK3GPR55 | |
| SCHEMBL31489305 | 0.70 | MKNK1 (0.38) | JAK2JAK1TYK2JAK3GPR55 | |
| SCHEMBL5992577 | 0.68 | CYP2D6 (0.51) | NPY5RHDAC4KCNH2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |