Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 4/20 | 0.31 |
| ▸ | JAK1 | P23458 | 3/20 | 0.31 |
| ▸ | TYK2 | P29597 | 3/20 | 0.31 |
| ▸ | JAK3 | P52333 | 3/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489373 | 1.00 | MKNK1 (0.38) | MKNK1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31489637 | 0.91 | MKNK1 (0.39) | MKNK1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31489570 | 0.89 | MKNK1 (0.40) | MKNK1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31489233 | 0.83 | MKNK1 (0.39) | MKNK1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31489513 | 0.80 | MKNK1 (0.40) | MKNK1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31489488 | 0.79 | MKNK1 (0.39) | MKNK1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL19555915 | 0.78 | MKNK1 (0.37) | MKNK1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31489235 | 0.74 | CCNE2 (0.33) | SMN1; SMN2KDM4EJAK2GPR55 | |
| SCHEMBL31489663 | 0.73 | JAK2 (0.34) | SMN1; SMN2KDM4EJAK2JAK1TYK2 | |
| SCHEMBL31489553 | 0.72 | CYP11B2 (0.40) | SMN1; SMN2KDM4EJAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |