Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 3/20 | 0.30 |
| ▸ | JAK1 | P23458 | 3/20 | 0.30 |
| ▸ | TYK2 | P29597 | 3/20 | 0.30 |
| ▸ | JAK3 | P52333 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489816 | 1.00 | CYP11B2 (0.40) | CYP11B2CYP11B1KDM4ESMN1; SMN2JAK2 | |
| SCHEMBL31489665 | 0.92 | CYP11B2 (0.38) | CYP11B2CYP11B1KDM4ESMN1; SMN2 | |
| SCHEMBL31489450 | 0.85 | CHEK1 (0.31) | — | |
| SCHEMBL31489407 | 0.85 | CHEK1 (0.31) | — | |
| SCHEMBL31489637 | 0.82 | MKNK1 (0.39) | KDM4ESMN1; SMN2JAK2JAK1TYK2 | |
| SCHEMBL31489266 | 0.81 | CYP17A1 (0.40) | CYP11B2CYP11B1JAK2JAK1TYK2 | |
| SCHEMBL31489758 | 0.80 | CYP11B1 (0.34) | CYP11B2CYP11B1 | |
| SCHEMBL31489575 | 0.77 | GABRA1 (0.32) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489349 | 0.77 | GABRA1 (0.32) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489235 | 0.76 | CCNE2 (0.33) | KDM4ESMN1; SMN2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |