Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.31 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
| ▸ | BCL6 | P41182 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867865 | 0.83 | LMNA (0.41) | LMNANOS3NOS2HTTKMT2A | |
| SCHEMBL14853133 | 0.83 | LMNA (0.41) | LMNANOS3NOS2HTTKMT2A | |
| SCHEMBL31489845 | 0.77 | HTT (0.38) | HTTKMT2AVRK1BCL6 | |
| SCHEMBL12377647 | 0.77 | HTT (0.38) | HTTKMT2AVRK1BCL6 | |
| SCHEMBL22809671 | 0.77 | NOS3 (0.38) | LMNANOS3NOS2NOS1DAO | |
| SCHEMBL24033512 | 0.76 | HTT (0.41) | LMNANOS3NOS2HTTKMT2A | |
| SCHEMBL31041294 | 0.76 | HTT (0.41) | LMNANOS3NOS2HTTKMT2A | |
| SCHEMBL13695116 | 0.74 | LMNA (0.37) | LMNANOS3NOS2HTTKMT2A | |
| SCHEMBL31489236 | 0.74 | DAO (0.32) | DAO | |
| SCHEMBL29431111 | 0.74 | HTT (0.35) | HTTKMT2AVRK1BCL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |