Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25252040 | 0.82 | LPL (0.36) | LPLLIPGIDO1TDO2ROCK1 | |
| SCHEMBL31489425 | 0.81 | JAK2 (0.31) | JAK2BTK | |
| SCHEMBL31489613 | 0.76 | JAK2 (0.34) | IDO1TDO2JAK2BTK | |
| SCHEMBL31489676 | 0.76 | JAK2 (0.34) | IDO1TDO2JAK2BTK | |
| SCHEMBL31489677 | 0.76 | JAK2 (0.34) | IDO1TDO2JAK2BTK | |
| SCHEMBL31489436 | 0.76 | JAK2 (0.33) | LPLLIPGJAK2BTK | |
| SCHEMBL31489454 | 0.75 | LPL (0.35) | LPLLIPGIDO1TDO2ROCK1 | |
| SCHEMBL31489632 | 0.74 | IRAK4 (0.35) | LPLLIPGIDO1TDO2IRAK4 | |
| SCHEMBL31489321 | 0.74 | KDM4E (0.40) | — | |
| SCHEMBL15175675 | 0.73 | LPL (0.36) | LPLLIPGIDO1TDO2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |