Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.33 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 4/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489548 | 0.87 | TDP2 (0.35) | PIK3CGPIK3CATDP2HSP90AA1HSP90AB1 | |
| SCHEMBL31489814 | 0.85 | PIK3CG (0.38) | CYP11B2CYP11B1PIK3CGPIK3CDPIK3CA | |
| SCHEMBL31489228 | 0.84 | TDP2 (0.32) | AAK1TDP2HSP90AA1HSP90AB1SUV39H2 | |
| SCHEMBL31489598 | 0.83 | EGLN2 (0.32) | AAK1HSP90AA1HSP90AB1 | |
| SCHEMBL31489435 | 0.82 | PIK3CG (0.33) | PIK3CGPIK3CDPAK4JAK1PIK3CA | |
| SCHEMBL31489597 | 0.82 | USP30 (0.36) | PIK3CGPIK3CDPAK4JAK1PIK3CA | |
| SCHEMBL31489812 | 0.81 | TDP2 (0.34) | PIK3CGPIK3CDPIK3CAPIK3CBAAK1 | |
| SCHEMBL31489388 | 0.80 | AAK1 (0.32) | CYP11B2CYP11B1AAK1 | |
| SCHEMBL31489552 | 0.79 | TDP2 (0.34) | TDP2 | |
| SCHEMBL31489834 | 0.78 | CSNK2A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |