SCHEMBL31489552

SCHEMBL31489552

CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nc2cc(-c3nc(Cl)ccc3F)ccn2n1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 4/20 0.34
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489812 0.84 TDP2 (0.34) TDP2APP
SCHEMBL31489427 0.84 APP (0.32) APP
SCHEMBL31489293 0.83 TDP2 (0.33) TDP2APP
SCHEMBL31489548 0.82 TDP2 (0.35) TDP2
SCHEMBL31489473 0.82 TDP2 (0.32) TDP2APP
SCHEMBL31507676 0.80 TDP2 (0.32) TDP2APP
SCHEMBL31489308 0.80 SSTR4 (0.34)
SCHEMBL31489435 0.79 PIK3CG (0.33) TDP2
SCHEMBL31489340 0.79 CYP11B2 (0.34) TDP2
SCHEMBL25440010 0.79 CSNK2A2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed