Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 6/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.33 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 5/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489340 | 0.82 | CYP11B2 (0.34) | PIK3CGPIK3CDAAK1PAK4JAK1 | |
| SCHEMBL20472618 | 0.82 | CSNK2A2 (0.33) | PIK3CGPIK3CDAAK1PAK4JAK1 | |
| SCHEMBL31489548 | 0.81 | TDP2 (0.35) | PIK3CGPIK3CATDP2USP30SUV39H2 | |
| SCHEMBL31489228 | 0.80 | TDP2 (0.32) | AAK1TDP2SUV39H2GPR119 | |
| SCHEMBL31489552 | 0.79 | TDP2 (0.34) | TDP2 | |
| SCHEMBL25439804 | 0.78 | TSHR (0.38) | TDP2SYKLMNAKMT2ASUV39H2 | |
| SCHEMBL31489812 | 0.77 | TDP2 (0.34) | PIK3CGPIK3CDAAK1PIK3CAPIK3CB | |
| SCHEMBL31489598 | 0.77 | EGLN2 (0.32) | AAK1GPR119 | |
| SCHEMBL31489293 | 0.77 | TDP2 (0.33) | TDP2 | |
| SCHEMBL31489473 | 0.77 | TDP2 (0.32) | TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |