Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | F9 | P00740 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15639486 | 0.71 | TGFBR1 (0.38) | KDM4ETGFBR1PIK3CDTNIKEGLN2 | |
| SCHEMBL31489179 | 0.70 | KDM4E (0.35) | KDM4EALDH1A1JAK2 | |
| SCHEMBL29655527 | 0.70 | EGLN2 (0.41) | KDM4EALDH1A1JAK2TGFBR1DYRK1A | |
| SCHEMBL18030717 | 0.68 | TGFBR1 (0.64) | TGFBR1 | |
| SCHEMBL22878940 | 0.68 | PIK3CD (0.37) | KDM4EALDH1A1TGFBR1DYRK1APIK3CD | |
| SCHEMBL24726642 | 0.68 | MAPK1 (0.41) | JAK2TGFBR1PIK3CDTNIKF9 | |
| SCHEMBL19762806 | 0.67 | IDO1 (0.50) | JAK2TGFBR1HSD17B1HSD17B2 | |
| SCHEMBL15640085 | 0.67 | EGLN2 (0.44) | JAK2TGFBR1EGLN2BACE1 | |
| SCHEMBL23291684 | 0.67 | TGFBR1 (0.44) | TGFBR1DYRK1APIK3CDTNIKSCD | |
| SCHEMBL23291682 | 0.67 | ALDH1A1 (0.40) | ALDH1A1TGFBR1PIK3CDTNIKSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |