Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489691 | 1.00 | HSP90AA1 (0.31) | HSP90AA1PIK3CAPIK3CGROCK2RIPK1 | |
| SCHEMBL31489721 | 0.96 | ROCK2 (0.32) | HSP90AA1PIK3CAPIK3CGROCK2RIPK1 | |
| SCHEMBL31489612 | 0.89 | RIPK1 (0.30) | RIPK1 | |
| SCHEMBL31489810 | 0.89 | RIPK1 (0.30) | RIPK1 | |
| SCHEMBL31489416 | 0.85 | RIPK1 (0.31) | PIK3CGROCK2RIPK1 | |
| SCHEMBL31489859 | 0.85 | RIPK1 (0.31) | PIK3CGROCK2RIPK1 | |
| SCHEMBL31489668 | 0.84 | TDP2 (0.31) | ROCK2RIPK1 | |
| SCHEMBL31489695 | 0.84 | TDP2 (0.31) | ROCK2RIPK1 | |
| SCHEMBL31489288 | 0.84 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL31489572 | 0.83 | PIK3CG (0.34) | PIK3CAPIK3CGROCK2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |