Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489702 | 1.00 | NTRK1 (0.33) | NTRK1PIK3CDPIK3CAPIK3CGTGFBR1 | |
| SCHEMBL31489840 | 0.89 | TDP2 (0.31) | NTRK1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489763 | 0.89 | TDP2 (0.31) | NTRK1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489395 | 0.87 | NTRK1 (0.31) | NTRK1 | |
| SCHEMBL31489386 | 0.86 | PIK3CG (0.35) | NTRK1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489516 | 0.86 | PIK3CG (0.35) | NTRK1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489660 | 0.86 | BRD4 (0.35) | NTRK1 | |
| SCHEMBL31489178 | 0.86 | — | — | |
| SCHEMBL31489827 | 0.85 | JAK2 (0.31) | NTRK1 | |
| SCHEMBL31489722 | 0.84 | NTRK1 (0.30) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |