Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489763 | 1.00 | TDP2 (0.31) | TDP2NTRK1ROCK2PIK3CDPIK3CA | |
| SCHEMBL31489395 | 0.93 | NTRK1 (0.31) | NTRK1RIPK1 | |
| SCHEMBL31489494 | 0.89 | NTRK1 (0.33) | NTRK1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489702 | 0.89 | NTRK1 (0.33) | NTRK1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489441 | 0.86 | RIPK1 (0.40) | TDP2PIK3CDPIK3CAPIK3CGRIPK1 | |
| SCHEMBL31489404 | 0.86 | RIPK1 (0.40) | TDP2PIK3CDPIK3CAPIK3CGRIPK1 | |
| SCHEMBL31489315 | 0.86 | ROCK2 (0.32) | ROCK2PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489860 | 0.83 | PIK3CD (0.32) | NTRK1ROCK2PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489338 | 0.82 | — | — | |
| SCHEMBL31489317 | 0.79 | PIK3CG (0.41) | PIK3CDPIK3CAPIK3CGRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |