SCHEMBL31489508

SCHEMBL31489508

COc1c(Br)ccn2nc(-n3c(C)ccc3C)nc12

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
NQO2 P16083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489218 0.82 KDM4E (0.40) KDM4E
SCHEMBL31489346 0.76 JAK2 (0.48) NQO2
SCHEMBL31489274 0.76
SCHEMBL31489477 0.75 UCHL1 (0.30)
SCHEMBL31489540 0.74 KDM4E (0.33) KDM4E
SCHEMBL31489219 0.68 PDE10A (0.33) KDM4E
SCHEMBL31489534 0.68 KDM4E (0.31) KDM4E
SCHEMBL31489573 0.68 KDM4E (0.40) KDM4ENQO2
SCHEMBL31489938 0.67 PDE10A (0.41) KDM4E
SCHEMBL31489689 0.67 AHR (0.50) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed