Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489531 | 0.82 | KDM4E (0.39) | KDM4E | |
| SCHEMBL31489486 | 0.81 | MAPT (0.33) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31489379 | 0.77 | KDM4E (0.37) | KDM4E | |
| SCHEMBL31489563 | 0.75 | EGFR (0.32) | SMN1; SMN2LMNA | |
| SCHEMBL31489689 | 0.72 | AHR (0.50) | KDM4EALDH1A1NPC1RAB9ANR4A1 | |
| SCHEMBL31489137 | 0.69 | KDM4E (0.30) | KDM4E | |
| SCHEMBL31489622 | 0.68 | KDM4E (0.39) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31489508 | 0.68 | KDM4E (0.36) | KDM4ENQO2 | |
| SCHEMBL31600705 | 0.67 | ALDH1A1 (0.37) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8387974 | 0.65 | MAPT (0.47) | KDM4EALDH1A1MAPTLMNANR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |