SCHEMBL31489559

SCHEMBL31489559

CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nc2cc(-c3cccc(Br)c3F)ccn2n1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 1/20 0.34
TDP2 O95551 2/20 0.32
BRD4 O60885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31507742 0.89 HSD17B14 (0.34) TDP2BRD4
SCHEMBL31489361 0.85 SSTR4 (0.31) SSTR4
SCHEMBL31489308 0.85 SSTR4 (0.34) SSTR4
SCHEMBL31507676 0.83 TDP2 (0.32) TDP2
SCHEMBL31507795 0.83 CSNK2A1 (0.32)
SCHEMBL31489745 0.82 BACE1 (0.36)
SCHEMBL25440010 0.82 CSNK2A2 (0.32)
SCHEMBL31507885 0.82 TDP2 (0.31) TDP2
SCHEMBL31489615 0.82 BACE1 (0.36)
SCHEMBL31489466 0.82 AAK1 (0.36) SSTR4TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed