SCHEMBL31489581

SCHEMBL31489581

Cc1nn([C@H](c2ccc(F)cc2)C(C)(F)F)cc1B1OC(C)(C)C(C)(C)O1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.36
LIPG Q9Y5X9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489273 1.00 LPL (0.36) LPLLIPG
SCHEMBL31489588 0.89 LPL (0.37) LPLLIPG
SCHEMBL31489214 0.78 FFAR1 (0.44) LPLLIPG
SCHEMBL31489328 0.78 FFAR1 (0.44) LPLLIPG
SCHEMBL31489944 0.75 NPC1 (0.32)
SCHEMBL31489284 0.75 NPC1 (0.32)
SCHEMBL31489863 0.74 PDK2 (0.34) LPLLIPG
SCHEMBL31489237 0.74 PDK2 (0.34) LPLLIPG
SCHEMBL23674273 0.74 FFAR1 (0.31) LPLLIPG
SCHEMBL18390323 0.72 FFAR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed