Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31406584 | 0.90 | PIK3CD (0.43) | PIK3CDPIK3CALMNAMAPTALDH1A1 | |
| SCHEMBL22029147 | 0.84 | PIK3CD (0.42) | PIK3CDPIK3CALMNAMAPTALDH1A1 | |
| SCHEMBL30826844 | 0.84 | PIK3CD (0.42) | PIK3CDPIK3CALMNAMAPTALDH1A1 | |
| SCHEMBL30708395 | 0.83 | PIK3CD (0.43) | PIK3CDPIK3CALMNAMAPTALDH1A1 | |
| SCHEMBL23974786 | 0.81 | PIK3CD (0.42) | PIK3CDPIK3CALMNAMAPTALDH1A1 | |
| SCHEMBL21734048 | 0.81 | PIK3CD (0.42) | PIK3CDPIK3CALMNAMAPTALDH1A1 | |
| SCHEMBL31491014 | 0.78 | PIK3CD (0.42) | PIK3CDPIK3CALMNAMAPTALDH1A1 | |
| SCHEMBL31491021 | 0.78 | APLNR (0.42) | PIK3CDPIK3CALMNAMAPTALDH1A1 | |
| SCHEMBL21542641 | 0.76 | DCTPP1 (0.47) | PIK3CDPIK3CAMAPTALDH1A1NPSR1 | |
| SCHEMBL24649502 | 0.76 | PIK3CA (0.41) | PIK3CDPIK3CALMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049274-A2 | TETRACYCLIC DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |