Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | RRM2 | P31350 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470025 | 0.88 | GAA (0.49) | KMT2AMAPTGAASMN1; SMN2LMNA | |
| SCHEMBL31491974 | 0.88 | ALDH1A1 (0.53) | KMT2AMAPTGAASMN1; SMN2LMNA | |
| SCHEMBL455106 | 0.84 | KMT2A (0.47) | KMT2AMAPTGAASMN1; SMN2LMNA | |
| SCHEMBL31492089 | 0.84 | TGM2 (0.46) | KMT2AMAPTGAASMN1; SMN2LMNA | |
| SCHEMBL14075826 | 0.82 | MAPT (0.56) | KMT2AMAPTGAASMN1; SMN2MEN1 | |
| SCHEMBL470031 | 0.82 | MAPT (0.56) | KMT2AMAPTGAASMN1; SMN2MEN1 | |
| SCHEMBL13560840 | 0.80 | ALDH1A1 (0.53) | KMT2AMAPTGAASMN1; SMN2LMNA | |
| SCHEMBL469854 | 0.79 | KDR (0.56) | KMT2AMAPTGAAMEN1NPC1 | |
| SCHEMBL10084818 | 0.79 | KMT2A (0.53) | KMT2AMAPTGAALMNAMEN1 | |
| SCHEMBL18938331 | 0.79 | CA1 (0.54) | KMT2AMAPTALDH1A1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025046420-A1 | COMPOUND TARGETING EGR-1 AND USE THEREOF FOR TREATMENT OF ATOPIC DERMATITIS | 주식회사 아제라메디 | 2025-03-06 | — | — | WO | disclosed |