Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21903966 | 1.00 | GPR35 (0.38) | GPR35NUDT1ALDH1A1DYRK1AHTT | |
| SCHEMBL1613412 | 0.79 | ALDH1A1 (0.37) | NUDT1ALDH1A1DYRK1AHTTGSK3B | |
| SCHEMBL29497257 | 0.73 | LATS1 (0.32) | — | |
| SCHEMBL21903872 | 0.72 | KDM1A (0.33) | ALDH1A1KDM1A | |
| SCHEMBL21903886 | 0.71 | AR (0.36) | GPR35ALDH1A1GSK3B | |
| SCHEMBL14025078 | 0.69 | POLB (0.53) | ALDH1A1DYRK1AMEN1KMT2AKDM1A | |
| SCHEMBL11172727 | 0.69 | ALDH1A1 (0.49) | GPR35ALDH1A1DYRK1AHTTMEN1 | |
| SCHEMBL21903939 | 0.69 | XDH (0.46) | GPR35DYRK1AKDM1AIDO1 | |
| SCHEMBL31492077 | 0.69 | XDH (0.46) | GPR35DYRK1AKDM1AIDO1 | |
| SCHEMBL28601707 | 0.66 | XDH (0.46) | GPR35ALDH1A1DYRK1AKDM1AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227054-B | ROCK kinase inhibitors | 切尔韦洛治疗有限责任公司 | 2025-04-11 | — | — | CN | disclosed |