SCHEMBL3149244

SCHEMBL3149244

Cc1cccc(C)c1OCc1cc(OC(=O)c2ccccc2)ccc1CCl

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.46
MAPT P10636 7/20 0.44
TDP1 Q9NUW8 3/20 0.44
MEN1 O00255 1/20 0.44
NPBWR1 P48145 2/20 0.42
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GLA P06280 1/20 0.42
GAA P10253 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
THRB P10828 2/20 0.40
MAOB P27338 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
PKM P14618 1/20 0.39
THRA P10827 1/20 0.39
ESR1 P03372 1/20 0.39
POLB P06746 1/20 0.38
ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3150527 0.87 LMNA (0.44) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL2291481 0.85 KMT2A (0.46) KMT2AMAPTTDP1MEN1NPBWR1
SCHEMBL1201013 0.83 KMT2A (0.47) KMT2AMAPTTDP1MEN1NPBWR1
SCHEMBL3147078 0.80 FFAR1 (0.39) TDP1ALDH1A1KDM4ESMN1; SMN2THRB
SCHEMBL1200733 0.78 KMT2A (0.41) KMT2AMAPTTDP1MEN1NPBWR1
SCHEMBL3155529 0.77 SCN8A (0.45) MAOBATM
SCHEMBL3149262 0.75 ALDH1A1 (0.37) KMT2AMAPTMEN1ALDH1A1GAA
SCHEMBL2295218 0.74 THRA (0.46) KMT2AMAPTMEN1ALDH1A1SMN1; SMN2
SCHEMBL8617350 0.73 SCN4A (0.42) ALDH1A1GAATHRBTHRAPOLB
SCHEMBL3144508 0.73 ALDH1A1 (0.33) KMT2AMAPTMEN1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2154123-B1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2013-10-23 EP disclosed
CN-101679171-B Method for producing benzaldehyde compound SUMITOMO CHEMICAL CO 2012-12-12 CN disclosed
US-7851659-B2 Method for producing benzaldehyde compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-14 US disclosed
US-20100234645-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-16 US disclosed
EP-2154123-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234645-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND NQO1, NQO2, NDUFC2 KMT2A 548/4885MAPT 4606/4885TDP1 2422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.