SCHEMBL31493009

SCHEMBL31493009

Cc1cc(O)nc(C(C)(F)CF)n1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31492995 0.81 HSP90AA1 (0.34) HSP90AA1HSP90AB1
SCHEMBL10889888 0.79 HSP90AA1 (0.39) HSP90AA1HSP90AB1
SCHEMBL30755868 0.79 LMNA (0.36) HSP90AA1HSP90AB1
SCHEMBL5219701 0.77 ALDH1A1 (0.33)
SCHEMBL11095538 0.71 KDM4E (0.32) HSP90AA1
SCHEMBL30755776 0.68 MEN1 (0.33)
SCHEMBL31493105 0.67 ALDH1A1 (0.48)
SCHEMBL20609571 0.65 CNR1 (0.36)
SCHEMBL609557 0.63 HSP90AA1 (0.39) HSP90AA1HSP90AB1
SCHEMBL9252957 0.63 HTT (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028365-A1 TYROSINE KINASE 2 INHIBITORS AND USES THEREOF BIOGEN MA INC (US) 2026-01-29 US disclosed
CN-119894879-A Tyrosine kinase 2 inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-04-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028365-A1 TYROSINE KINASE 2 INHIBITORS AND USES THEREOF TYK2, ERBB2, ROS1 HSP90AA1 1663/4885HSP90AB1 981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.