Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30755776 | 0.87 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL10889888 | 0.85 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL5219701 | 0.83 | ALDH1A1 (0.33) | MAPTCYP2C9MEN1KMT2A | |
| SCHEMBL31493009 | 0.81 | HSP90AA1 (0.31) | HSP90AA1HSP90AB1 | |
| SCHEMBL31581581 | 0.78 | — | — | |
| SCHEMBL11095538 | 0.77 | KDM4E (0.32) | HSP90AA1LMNAKMT2A | |
| SCHEMBL31493035 | 0.75 | NOS3 (0.45) | HSP90AA1HSP90AB1DHODHKCNH2CYP2D6 | |
| SCHEMBL30632665 | 0.75 | LMNA (0.40) | HSP90AA1HSP90AB1DHODHKCNH2CYP2D6 | |
| SCHEMBL26685839 | 0.75 | LMNA (0.40) | HSP90AA1HSP90AB1DHODHKCNH2CYP2D6 | |
| SCHEMBL31543131 | 0.75 | NOS3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894879-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-119866338-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-119654322-A | TYK2 inhibitors | 渤健马萨诸塞州股份有限公司 | 2025-03-18 | — | — | CN | disclosed |