Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8456712 | 0.91 | ALDH1A1 (0.62) | ALDH1A1LMNAMAPTKCNH2DRD2 | |
| SCHEMBL13264901 | 0.91 | ALDH1A1 (0.62) | ALDH1A1LMNAMAPTKCNH2DRD2 | |
| SCHEMBL2480658 | 0.90 | KCNH2 (0.55) | ALDH1A1LMNAMAPTKCNH2DRD2 | |
| SCHEMBL378659 | 0.90 | KCNH2 (0.55) | ALDH1A1LMNAMAPTKCNH2DRD2 | |
| SCHEMBL6228523 | 0.86 | MAPT (0.65) | ALDH1A1LMNAMAPTKCNH2DRD2 | |
| SCHEMBL28180185 | 0.84 | MAPT (0.56) | ALDH1A1LMNAMAPTKCNH2DRD2 | |
| SCHEMBL519168 | 0.84 | DRD2 (0.58) | ALDH1A1MAPTKCNH2DRD2DRD4 | |
| SCHEMBL23412608 | 0.83 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTKCNH2DRD2 | |
| SCHEMBL7162702 | 0.83 | MAPT (0.56) | ALDH1A1LMNAMAPTKCNH2DRD2 | |
| SCHEMBL11155200 | 0.83 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTKCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076236-A1 | METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE | Design Therapeutics, Inc. (US) | 2025-04-10 | — | — | WO | disclosed |