Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 2/20 | 0.46 |
| ▸ | CLK2 | P49760 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31494404 | 0.86 | MAPT (0.44) | RAB9ANPC1CHRM2CHRM5CHRM1 | |
| SCHEMBL31494432 | 0.84 | GAA (0.53) | CLK4RAB9ANPC1MAPK1LMNA | |
| SCHEMBL31494445 | 0.84 | CHRM2 (0.44) | RAB9ANPC1CHRM2CHRM5CHRM1 | |
| SCHEMBL27218796 | 0.82 | MAPT (0.45) | RAB9ANPC1CHRM2CHRM5CHRM1 | |
| SCHEMBL31494431 | 0.82 | RAB9A (0.45) | RAB9ANPC1CHRM2CHRM5CHRM1 | |
| SCHEMBL31494450 | 0.80 | MAPT (0.47) | RAB9ANPC1CHRM2CHRM5CHRM1 | |
| SCHEMBL31494419 | 0.78 | NPC1 (0.46) | RAB9ANPC1CHRM2CHRM5CHRM1 | |
| SCHEMBL27218642 | 0.77 | RAB9A (0.47) | RAB9ANPC1CHRM2CHRM5CHRM1 | |
| SCHEMBL31494452 | 0.76 | MAPK1 (0.45) | CLK4RAB9ANPC1CHRM2CHRM5 | |
| SCHEMBL31494388 | 0.76 | MAPT (0.54) | RAB9ANPC1MAPK1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232448-B1 | AGONISTS OF FREE FATTY ACID RECEPTOR 1 AND THEIR USE IN DISEASES ASSOCIATED WITH SAID RECEPTOR | Halo Therapeutics Ltd (GB) | 2025-05-07 | — | — | EP | disclosed |
| EP-3956323-B1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | Halo Therapeutics Ltd (GB) | 2025-03-05 | — | — | EP | disclosed |