Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27218848 | 0.90 | SIRT2 (0.52) | ALDH1A1L3MBTL1TDP1HDAC1HDAC2 | |
| SCHEMBL27218694 | 0.90 | HDAC1 (0.49) | ALDH1A1L3MBTL1TDP1ATMHDAC1 | |
| SCHEMBL27218682 | 0.88 | S1PR1 (0.45) | ALDH1A1HDAC1HDAC2HDAC8RAB9A | |
| SCHEMBL27218808 | 0.85 | RAB9A (0.50) | ALDH1A1L3MBTL1TDP1ATMHDAC1 | |
| SCHEMBL29808217 | 0.83 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1TDP1ATMHDAC1 | |
| SCHEMBL27218893 | 0.80 | S1PR1 (0.47) | ALDH1A1L3MBTL1HDAC1HDAC2HDAC8 | |
| SCHEMBL27218812 | 0.80 | SIRT2 (0.52) | ALDH1A1L3MBTL1TDP1ATMHDAC1 | |
| SCHEMBL27218707 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1L3MBTL1TDP1ATMHDAC1 | |
| SCHEMBL31494416 | 0.75 | RAB9A (0.54) | ALDH1A1L3MBTL1TDP1ATMHDAC1 | |
| SCHEMBL29808136 | 0.73 | TDP1 (0.50) | ALDH1A1L3MBTL1TDP1ATMHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232448-B1 | AGONISTS OF FREE FATTY ACID RECEPTOR 1 AND THEIR USE IN DISEASES ASSOCIATED WITH SAID RECEPTOR | Halo Therapeutics Ltd (GB) | 2025-05-07 | — | — | EP | disclosed |
| EP-3956323-B1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | Halo Therapeutics Ltd (GB) | 2025-03-05 | — | — | EP | disclosed |