Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27218814 | 0.89 | LMNA (0.55) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL31494430 | 0.86 | SMN1; SMN2 (0.72) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL27218734 | 0.86 | S1PR1 (0.46) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL29808136 | 0.82 | TDP1 (0.50) | RAB9ANPC1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL27218886 | 0.76 | SMN1; SMN2 (0.70) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL31494429 | 0.75 | ALDH1A1 (0.47) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL27218688 | 0.75 | ALDH1A1 (0.62) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL27218936 | 0.74 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL27218668 | 0.74 | SMN1; SMN2 (0.49) | RAB9ANPC1SMN1; SMN2LMNATDP1 | |
| SCHEMBL27218874 | 0.73 | HTT (0.69) | RAB9ANPC1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232448-B1 | AGONISTS OF FREE FATTY ACID RECEPTOR 1 AND THEIR USE IN DISEASES ASSOCIATED WITH SAID RECEPTOR | Halo Therapeutics Ltd (GB) | 2025-05-07 | — | — | EP | disclosed |
| EP-3956323-B1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | Halo Therapeutics Ltd (GB) | 2025-03-05 | — | — | EP | disclosed |