SCHEMBL31494749

SCHEMBL31494749

C=C(CCCCC)C(C)Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.45
HPGD P15428 1/20 0.44
EPHX2 P34913 1/20 0.43
TRPA1 O75762 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
SIGMAR1 Q99720 1/20 0.41
PSMB5 P28074 1/20 0.41
FAAH O00519 2/20 0.40
MAOA P21397 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13622893 0.80 HPGD (0.50) HPGDTRPA1SIGMAR1MAOASLC6A2
SCHEMBL9332747 0.79 EPHX2 (0.53) CSNK1EHPGDEPHX2MEN1KMT2A
SCHEMBL932749 0.79 EPHX2 (0.53) CSNK1EHPGDEPHX2MEN1KMT2A
SCHEMBL26161558 0.77 CSNK1E (0.49) CSNK1ETRPA1SIGMAR1MAOASLC6A2
SCHEMBL15880312 0.76 ASAH1 (0.47) EPHX2
SCHEMBL15880443 0.75 ASAH1 (0.49) EPHX2MEN1KMT2A
SCHEMBL9068432 0.75 LTA4H (0.49) HPGDEPHX2MEN1KMT2APSMB5
SCHEMBL8728626 0.75 LTA4H (0.49) HPGDEPHX2MEN1KMT2APSMB5
SCHEMBL14301469 0.74 TRPA1 (0.50) HPGDTRPA1SIGMAR1MAOASLC6A2
SCHEMBL13622891 0.72 TAAR1 (0.50) HPGDTRPA1SIGMAR1MAOASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751186-A Synthesis method of beta, gamma unsaturated ketone compound 中国科学院兰州化学物理研究所 2025-04-04 CN disclosed