Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 6/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31494808 | 0.87 | MAT2A (0.40) | MALT1MAT2ARXFP1TP53MAPT | |
| SCHEMBL31494874 | 0.87 | WEE1 (0.42) | MALT1MAT2AGRIN2DGRIN3BGRIA1 | |
| SCHEMBL31494904 | 0.86 | CCNE2 (0.38) | MALT1MAT2AGRIN2DGRIN3BGRIA1 | |
| SCHEMBL31494909 | 0.85 | MAT2A (0.35) | MAT2AGABRA1GABRA5GRIN2DGRIN3B | |
| SCHEMBL31494886 | 0.84 | MAT2A (0.36) | MAT2AGABRA1GABRA5GRIN2DGRIN3B | |
| SCHEMBL31494906 | 0.84 | MAPT (0.47) | MALT1MAT2AMAPTTHRB | |
| SCHEMBL31494841 | 0.84 | MAT2A (0.53) | MAT2AGABRA1GABRA5RXFP1MAPT | |
| SCHEMBL31494800 | 0.83 | MAT2A (0.40) | MAT2AGABRA1GABRA5RXFP1MAPT | |
| SCHEMBL31494799 | 0.83 | PDE4A (0.39) | MAT2ATP53MAPTCYP1A2IDH1 | |
| SCHEMBL31494872 | 0.83 | TP53 (0.46) | MAT2ARXFP1TP53MAPTGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | claimed |
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | disclosed |