Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | PDE8A | O60658 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31495044 | 0.88 | MAT2A (0.39) | MAT2AIDO1GABRA5GABRA1GRIN2D | |
| SCHEMBL31494841 | 0.88 | MAT2A (0.53) | MAT2AIDO1GABRA5GABRA1GRIN2D | |
| SCHEMBL31494874 | 0.86 | WEE1 (0.42) | MAT2AGRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL31494904 | 0.85 | CCNE2 (0.38) | MAT2AGRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL31494909 | 0.84 | MAT2A (0.35) | MAT2AGABRA5GABRA1GRIN2DGRIN3B | |
| SCHEMBL31494808 | 0.84 | MAT2A (0.40) | MAT2AGRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL31494851 | 0.83 | MALT1 (0.38) | MAT2AGABRA5GABRA1GRIN2DGRIN3B | |
| SCHEMBL31494799 | 0.82 | PDE4A (0.39) | MAT2APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL31494966 | 0.82 | MAT2A (0.39) | MAT2AGRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL31495085 | 0.81 | ADORA2B (0.44) | MAT2AMEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | claimed |
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | disclosed |