Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 4/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31494874 | 0.88 | WEE1 (0.42) | MAT2AGRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL31494904 | 0.87 | CCNE2 (0.38) | MAT2AGRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL31494808 | 0.86 | MAT2A (0.40) | MAT2AGRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL31494851 | 0.85 | MALT1 (0.38) | MAT2AGRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL31494800 | 0.84 | MAT2A (0.40) | MAT2AGRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL31494799 | 0.84 | PDE4A (0.39) | MAT2AHCAR1 | |
| SCHEMBL31494906 | 0.83 | MAPT (0.47) | MAT2A | |
| SCHEMBL31494860 | 0.83 | MAT2A (0.47) | MAT2AGRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL31495085 | 0.83 | ADORA2B (0.44) | MAT2ATDP2ADORA2B | |
| SCHEMBL31494841 | 0.82 | MAT2A (0.53) | MAT2AGRIN2DGRIN3BGRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | claimed |
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | disclosed |