Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.54 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3868582 | 0.83 | PDK1 (0.53) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL3863607 | 0.83 | PDK1 (0.53) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL29277598 | 0.80 | PDK1 (0.50) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL29849418 | 0.77 | CHRM1 (0.60) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL4329059 | 0.77 | PDK1 (0.71) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL30524578 | 0.77 | CHRM1 (0.60) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL13169241 | 0.77 | CCR5 (0.51) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL31393228 | 0.75 | HTR2C (0.58) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL3662621 | 0.75 | HTR2C (0.58) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL4329419 | 0.75 | PDK1 (0.56) | PDK1PDK2PDK3PDK4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4549438-A1 | FIVE-MEMBERED AND SIX-MEMBERED NITROGEN-CONTAINING COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF | Hangzhou Synrx Therapeutics Biomedical Technology Co., Ltd. (CN) | 2025-05-07 | — | — | EP | disclosed |