Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31495824 | 0.74 | LOXL2 (0.34) | LOXL2 | |
| SCHEMBL31495838 | 0.72 | SSTR4 (0.30) | — | |
| SCHEMBL31495900 | 0.70 | LOXL2 (0.35) | LOXL2 | |
| SCHEMBL12093432 | 0.62 | LOXL2 (0.47) | LOXL2 | |
| SCHEMBL29450783 | 0.62 | LOXL2 (0.47) | LOXL2 | |
| SCHEMBL31495806 | 0.61 | ENPP3 (0.30) | — | |
| SCHEMBL26982160 | 0.61 | AHR (0.31) | — | |
| SCHEMBL5227075 | 0.59 | CHRM2 (0.43) | — | |
| SCHEMBL31107785 | 0.58 | LOXL2 (0.36) | LOXL2 | |
| SCHEMBL24216729 | 0.58 | KDM1A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250120961-A1 | P53 MODULATORS | NESTED THERAPEUTICS INC (US) | 2025-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250120961-A1 | P53 MODULATORS | TP53, TP53BP1, MDM2 | LOXL2 4365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.