Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 6/20 | 0.40 |
| ▸ | MASP2 | O00187 | 3/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | KLK1 | P06870 | 2/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3149688 | 1.00 | KLKB1 (0.40) | KLKB1MASP2F7FURINNAMPT | |
| SCHEMBL3148667 | 0.90 | KLKB1 (0.41) | KLKB1MASP2F7FURINNAMPT | |
| SCHEMBL3149326 | 0.90 | KLKB1 (0.41) | KLKB1MASP2F7FURINNAMPT | |
| SCHEMBL3148655 | 0.90 | KLKB1 (0.41) | KLKB1MASP2F7FURINNAMPT | |
| SCHEMBL13416201 | 0.89 | KLKB1 (0.39) | KLKB1MASP2F7FURINNAMPT | |
| SCHEMBL3149682 | 0.85 | MASP2 (0.43) | KLKB1MASP2F7FURINNAMPT | |
| SCHEMBL3141379 | 0.85 | KLKB1 (0.43) | KLKB1MASP2F7FURINKLK1 | |
| SCHEMBL3141397 | 0.85 | KLKB1 (0.43) | KLKB1MASP2F7FURINKLK1 | |
| SCHEMBL1431904 | 0.85 | MASP2 (0.40) | KLKB1MASP2F7FURINNAMPT | |
| SCHEMBL1431907 | 0.85 | MASP2 (0.40) | KLKB1MASP2F7FURINNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | VANTIA LIMITED (GB) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | CHRM1, ARG1, ARG2 | KLKB1 3491/4885MASP2 3039/4885F7 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.