Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30752994 | 0.83 | ADORA1 (0.44) | P2RX4 | |
| SCHEMBL30752887 | 0.82 | KDM1A (0.46) | NOTUMHSD17B3P2RX4 | |
| SCHEMBL31318504 | 0.79 | SLC22A12 (0.42) | NOTUMHSD17B3SIRT3 | |
| SCHEMBL31318560 | 0.78 | SIRT3 (0.41) | SIRT3 | |
| SCHEMBL31318523 | 0.76 | SLC22A12 (0.44) | SIRT3 | |
| SCHEMBL31318539 | 0.76 | SLC22A12 (0.50) | SIRT3P2RX4 | |
| SCHEMBL31318516 | 0.76 | SLC22A12 (0.43) | SIRT3 | |
| SCHEMBL31318493 | 0.75 | LMNA (0.42) | SIRT3 | |
| SCHEMBL31318544 | 0.75 | SIRT3 (0.41) | SIRT3 | |
| SCHEMBL31318517 | 0.75 | SIRT3 (0.41) | SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585261-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |