Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | PDE4A | P27815 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30970711 | 0.81 | ADORA1 (0.38) | PRMT5WDR77HTTPDE3BPDE3A | |
| SCHEMBL27002463 | 0.81 | ADORA1 (0.38) | PRMT5WDR77HTTPDE3BPDE3A | |
| SCHEMBL27002284 | 0.81 | PRMT5 (0.35) | PRMT5WDR77HTTPDE3BPDE3A | |
| SCHEMBL29915079 | 0.81 | PRMT5 (0.35) | PRMT5WDR77HTTPDE3BPDE3A | |
| SCHEMBL31496831 | 0.79 | PRMT5 (0.60) | PRMT5WDR77CYP2C9TSHRCYP2C19 | |
| SCHEMBL30752851 | 0.78 | PRMT5 (0.39) | PRMT5WDR77HTTCYP2C9TSHR | |
| SCHEMBL30752919 | 0.78 | PARP1 (0.32) | PARP1 | |
| SCHEMBL23087315 | 0.77 | AR (0.41) | PRMT5WDR77HTTPDE3BPDE3A | |
| SCHEMBL25219373 | 0.76 | PRMT5 (0.35) | PRMT5WDR77HTTPDE3BPDE3A | |
| SCHEMBL30833177 | 0.76 | PRMT5 (0.35) | PRMT5WDR77HTTPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585261-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |