Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 5/20 | 0.60 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.60 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29735166 | 0.86 | PRMT5 (0.64) | PRMT5WDR77PARP1RXFP1KDM4E | |
| SCHEMBL23087658 | 0.86 | PRMT5 (0.64) | PRMT5WDR77PARP1RXFP1KDM4E | |
| SCHEMBL30753115 | 0.85 | PRMT5 (0.47) | PRMT5WDR77PARP1KDM4ELMNA | |
| SCHEMBL29915065 | 0.84 | PRMT5 (0.61) | PRMT5WDR77PARP1CYP1B1RXFP1 | |
| SCHEMBL27002364 | 0.84 | PRMT5 (0.61) | PRMT5WDR77PARP1CYP1B1RXFP1 | |
| SCHEMBL29915208 | 0.84 | PRMT5 (0.64) | PRMT5WDR77PARP1CYP1B1TYR | |
| SCHEMBL27002267 | 0.84 | PRMT5 (0.64) | PRMT5WDR77PARP1CYP1B1TYR | |
| SCHEMBL30752851 | 0.83 | PRMT5 (0.39) | PRMT5WDR77PARP1KDM4EHSD17B10 | |
| SCHEMBL31496856 | 0.82 | PRMT5 (0.55) | PRMT5WDR77PARP1CYP1B1KDM4E | |
| SCHEMBL29735278 | 0.82 | PRMT5 (0.69) | PRMT5WDR77PARP1CYP1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585261-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |