Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20522110 | 1.00 | PKM (0.47) | PKMALDH1A1KMT2APTK2BKEAP1 | |
| SCHEMBL12466431 | 0.87 | ALDH1A1 (0.47) | PKMALDH1A1KMT2APTK2BKEAP1 | |
| SCHEMBL25527327 | 0.85 | PKM (0.46) | PKMALDH1A1KMT2APTK2BKEAP1 | |
| SCHEMBL7959141 | 0.85 | PTPN11 (0.51) | PKMALDH1A1KMT2APTK2BKEAP1 | |
| SCHEMBL1505106 | 0.84 | ALDH1A1 (0.49) | PKMALDH1A1KMT2APTK2BKEAP1 | |
| SCHEMBL2449519 | 0.83 | PTPN11 (0.63) | ALDH1A1KMT2APTPN11S1PR3PTPN1 | |
| SCHEMBL20521893 | 0.82 | TSHR (0.50) | ALDH1A1KMT2APTPN11S1PR3SYK | |
| SCHEMBL31497228 | 0.82 | GAA (0.61) | ALDH1A1HTR2AHTR2CGAATSHR | |
| SCHEMBL987385 | 0.82 | GAA (0.61) | ALDH1A1HTR2AHTR2CGAATSHR | |
| SCHEMBL4138843 | 0.81 | PKM (0.71) | PKMKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136858-A | Compounds useful as ALCAT1 inhibitors | 中美博瑞纳制药有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-110709394-B | Compounds useful as ALCAT1 inhibitors | 中美博瑞纳制药有限公司 | 2025-02-21 | — | — | CN | disclosed |