Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 7/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16324457 | 0.75 | HDAC1 (0.30) | HDAC1 | |
| SCHEMBL16323148 | 0.75 | — | — | |
| SCHEMBL21527333 | 0.73 | ALDH1A1 (0.56) | TGFBR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16324458 | 0.72 | HDAC1 (0.32) | HDAC1 | |
| SCHEMBL16364957 | 0.71 | HDAC1 (0.34) | TGFBR1HDAC1 | |
| SCHEMBL18357661 | 0.70 | SLC22A12 (0.38) | TGFBR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16364940 | 0.70 | ENPP2 (0.31) | — | |
| SCHEMBL23099477 | 0.69 | ALDH1A1 (0.34) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18357705 | 0.68 | KMT2A (0.37) | HDAC1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16365220 | 0.67 | POLB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490501-A | Imidazole bicyclic compounds, preparation method and application thereof | 合肥医工医药股份有限公司 | 2025-02-21 | — | — | CN | disclosed |