Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
| ▸ | GRK5 | P34947 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18357661 | 0.85 | SLC22A12 (0.38) | KMT2ACYP2C9CYP3A4CYP2C19RAB9A | |
| SCHEMBL18365740 | 0.76 | CYP2C9 (0.34) | KMT2ACYP2C9CYP3A4CYP2C19RAB9A | |
| SCHEMBL18357422 | 0.76 | DAPK3 (0.41) | KMT2AMAPTDAPK3JAK2PRKD3 | |
| SCHEMBL16447554 | 0.75 | RAB9A (0.45) | KMT2ACYP2C9CYP3A4RAB9AMAPT | |
| SCHEMBL24030244 | 0.71 | MAPK1 (0.35) | KMT2ARAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL16945271 | 0.69 | MAPT (0.43) | KMT2ARAB9AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL12295206 | 0.68 | CYP2C9 (0.67) | KMT2ACYP2C9CYP3A4CYP2C19RAB9A | |
| SCHEMBL31497685 | 0.68 | TGFBR1 (0.34) | CYP2C9CYP3A4CYP2C19HDAC1 | |
| SCHEMBL23099415 | 0.68 | CYP1A2 (0.42) | KMT2ACYP2C9CYP2C19RAB9ACYP1A2 | |
| SCHEMBL23099566 | 0.68 | CYP1A2 (0.42) | KMT2ACYP2C9CYP2C19RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230014173-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2023-01-19 | — | — | US | disclosed |
| US-11180472-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2021-11-23 | — | — | US | disclosed |
| US-20200239434-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2020-07-30 | — | — | US | disclosed |
| US-20190330189-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2019-10-31 | — | — | US | disclosed |
| US-10364232-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2019-07-30 | — | — | US | disclosed |
| US-20180186768-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2018-07-05 | — | — | US | disclosed |
| US-20180186768-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2018-07-05 | — | — | US | disclosed |
| WO-2017001660-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2017-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180472-B2 | Antibacterial compounds | FDPS, SQOR, NDUFS3 | KMT2A 4441/4885CYP2C9 1874/4885CYP3A4 1015/4885 |
| US-20190330189-A1 | ANTIBACTERIAL COMPOUNDS | FDPS, SQOR, NDUFS3 | KMT2A 4441/4885CYP2C9 1874/4885CYP3A4 1015/4885 |
| US-10364232-B2 | Antibacterial compounds | FDPS, SQOR, NDUFS3 | KMT2A 4441/4885CYP2C9 1874/4885CYP3A4 1015/4885 |
| US-20180186768-A1 | Antibacterial Compounds | FDPS, SQOR, NDUFS3 | KMT2A 4441/4885CYP2C9 1874/4885CYP3A4 1015/4885 |
| US-20230014173-A1 | Antibacterial Compounds | FDPS, SQOR, NDUFS3 | KMT2A 4441/4885CYP2C9 1874/4885CYP3A4 1015/4885 |
| US-20200239434-A1 | ANTIBACTERIAL COMPOUNDS | FDPS, SQOR, NDUFS3 | KMT2A 4441/4885CYP2C9 1874/4885CYP3A4 1015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.