Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901003 | 0.82 | NR1H2 (0.65) | NR1H2CYP3A4HSD17B10ALOX15HIF1A | |
| SCHEMBL11653143 | 0.77 | NR1H2 (0.58) | NR1H2CYP3A4HSD17B10ALOX15HIF1A | |
| SCHEMBL9721400 | 0.77 | NR1H2 (0.58) | NR1H2CYP3A4HSD17B10ALOX15HIF1A | |
| SCHEMBL275952 | 0.77 | — | — | |
| SCHEMBL3891211 | 0.74 | ACHE (0.47) | LMNAALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL27464590 | 0.74 | PTGS2 (0.55) | NR1H2CYP3A4HSD17B10ALOX15HIF1A | |
| SCHEMBL11673519 | 0.74 | ESR1 (0.65) | NR1H2CYP3A4HSD17B10ALOX15HIF1A | |
| SCHEMBL778098 | 0.72 | ACHE (0.41) | ALDH1A1MEN1MAPTKMT2ACA2 | |
| SCHEMBL19520463 | 0.72 | HSD17B10 (0.67) | NR1H2CYP3A4HSD17B10ALOX15HIF1A | |
| SCHEMBL14373966 | 0.72 | LMNA (0.44) | HSD17B10LMNAALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504528-A | Method for carrying out disulfide bond reversible exchange under mild biological compatibility condition | 南京耀佳源生物医药有限公司 | 2025-02-25 | — | — | CN | disclosed |