Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2499667 | 0.75 | KEAP1 (0.47) | NAMPTKEAP1CYP2C9HDAC1HDAC8 | |
| SCHEMBL1355263 | 0.75 | DYRK1A (0.53) | NAMPTKEAP1TGFBR1MET | |
| SCHEMBL13996528 | 0.74 | KEAP1 (0.50) | NAMPTKEAP1HDAC1HDAC8HDAC6 | |
| SCHEMBL10055033 | 0.73 | LMNA (0.61) | ALDH1A1SMN1; SMN2L3MBTL1P4HTMLMNA | |
| SCHEMBL6419238 | 0.73 | LMNA (0.61) | ALDH1A1SMN1; SMN2L3MBTL1P4HTMLMNA | |
| SCHEMBL1830448 | 0.73 | DYRK1A (0.71) | KEAP1TGFBR1MET | |
| SCHEMBL21167452 | 0.72 | MET (0.54) | NAMPTKEAP1TGFBR1MET | |
| SCHEMBL173877 | 0.71 | NAMPT (0.86) | NAMPTCYP2C9 | |
| SCHEMBL17790192 | 0.70 | KEAP1 (0.62) | NAMPTKEAP1 | |
| SCHEMBL17196187 | 0.70 | KEAP1 (0.57) | NAMPTKEAP1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3577116-B1 | DERIVATIVES OF N-CYCLOALKYL/HETEROCYCLOALKYL-4-(IMIDAZO[1,2-A]PYRIDINE)PYRIMIDIN-2-AMINE AS THERAPEUTIC AGENTS | CHANGZHOU QIANHONG BIO PHARMA CO LTD (CN) | 2025-04-23 | — | — | EP | disclosed |