SCHEMBL315016

SCHEMBL315016

COc1ccc[c]c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11460691 0.82 APP (0.44)
SCHEMBL16958470 0.78 KCNH2 (0.34)
SCHEMBL6766726 0.77 IRAK4 (0.38)
SCHEMBL1069301 0.77 ALDH1A1 (0.44)
SCHEMBL17046388 0.77 L3MBTL1 (0.40)
SCHEMBL28621595 0.77 ALDH1A1 (0.38)
SCHEMBL2885322 0.76 CA1 (0.50)
SCHEMBL9673815 0.75 KDM4E (0.49)
SCHEMBL62201 0.74
SCHEMBL123985 0.74 CA1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 809 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240208902-A1 CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2024-06-27 US claimed
US-20240002344-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION FIBROGEN, INC. 2024-01-04 US claimed
US-11802111-B2 Cyclobutyl amide monoacylglycerol lipase modulators JANSSEN PHARMACEUTICA NV (BE) 2023-10-31 US claimed
EP-4217062-A1 CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN Pharmaceutica NV (BE) 2023-08-02 EP claimed
EP-4204400-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION Fibrogen, Inc. (US) 2023-07-05 EP claimed
CN-116348450-A Compounds, compositions and methods for histone lysine demethylase inhibition 菲布罗根有限公司 2023-06-27 CN claimed
EP-3867238-B1 PROTEIN TYROSINE PHOSPHATASE INHIBITORS ARRAY BIOPHARMA INC (US) 2023-06-07 EP claimed
CN-112368272-B SHP2 inhibitors and uses thereof 苏州浦合医药科技有限公司 2023-04-21 CN claimed
US-11597728-B2 Monoacylglycerol lipase modulators JANSSEN PHARMACEUTICA NV (BE) 2023-03-07 US claimed
US-20220202818-A1 COMBINATION WITH CHECKPOINT INHIBITORS TO TREAT CANCER NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-06-30 US claimed
US-4314015-A Electrophotographic sensitive materials containing disazo compounds RICOH CO., LTD. (JP) 1982-02-02 US claimed
US-4299896-A Electrophotographic sensitive materials containing a disazo pigment RICOH CO., LTD. (JP) 1981-11-10 US claimed
US-4293628-A Electrophotographic elements containing disazo compounds RICOH CO., LTD. (JP) 1981-10-06 US claimed
US-4279981-A Electrophotographic elements containing trisazo compounds RICOH COMPANY, LTD. (JP) 1981-07-21 US claimed
US-4272598-A STYRYL DYES RICOH CO., LTD. (JP) 1981-06-09 US claimed
US-4260672-A Electrophotographic sensitive element having a photoconductive disazo pigment RICOH COMPANY, LTD. (JP) 1981-04-07 US claimed
US-4251614-A CARBAZOLE DERIVATIVES RICOH COMPANY, LTD. (JP) 1981-02-17 US claimed
US-4251613-A LAMINATE OF CONDUCTIVE SUPPORT AND PHOTOSENSITIVE LAYER RICOH COMPANY, LTD. (JP) 1981-02-17 US claimed
EP-0012611-A2 Electrophotographic element Ricoh Company, Ltd (JP) 1980-06-25 EP claimed
US-4010162-A Substituted phenanthroline pigments ALLIED CHEMICAL CORPORATION (US) 1977-03-01 US claimed