Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.40 |
| ▸ | TSHR | P16473 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | USP2 | O75604 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31501684 | 0.82 | TSHR (0.48) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| SCHEMBL30456080 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| SCHEMBL25269396 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| SCHEMBL31501723 | 0.73 | PIK3R1 (0.38) | ALDH1A1HPGDCYP2D6CYP3A4CYP2C19 | |
| SCHEMBL31501698 | 0.72 | ROCK2 (0.40) | CYP3A4PIK3CAMTORPIK3R1 | |
| SCHEMBL31501633 | 0.72 | KCNH2 (0.44) | MEN1KMT2APIK3CAMTORPIK3R1 | |
| SCHEMBL31501699 | 0.70 | HRH4 (0.40) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| SCHEMBL31501688 | 0.70 | MAOB (0.35) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| SCHEMBL31027440 | 0.68 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| SCHEMBL13633931 | 0.67 | PAK4 (0.52) | ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | BALA THERAPEUTICS, INC. | 2025-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | MLLT1, MEN1, BMI1 | ALDH1A1 3650/4885HSD17B10 1866/4885HPGD 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.