Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22495244 | 1.00 | LMNA (0.54) | LMNAMAPTNPC1RAB9ATSHR | |
| SCHEMBL30172104 | 0.94 | MAPT (0.49) | LMNAMAPTNPC1RAB9ATSHR | |
| SCHEMBL22574512 | 0.93 | MAPT (0.52) | LMNAMAPTNPC1RAB9ATSHR | |
| SCHEMBL22495453 | 0.90 | DGAT1 (0.53) | LMNAMAPTNPC1RAB9ATSHR | |
| SCHEMBL31504192 | 0.90 | DGAT1 (0.53) | LMNAMAPTNPC1RAB9ATSHR | |
| SCHEMBL22495261 | 0.89 | NAMPT (0.55) | LMNAMAPTNPC1RAB9ATSHR | |
| SCHEMBL31504234 | 0.89 | NAMPT (0.55) | LMNAMAPTNPC1RAB9ATSHR | |
| SCHEMBL31504250 | 0.88 | DRD4 (0.46) | LMNAMAPTNPC1RAB9ATSHR | |
| SCHEMBL22495258 | 0.88 | DRD4 (0.46) | LMNAMAPTNPC1RAB9ATSHR | |
| SCHEMBL22495336 | 0.88 | ALDH1A1 (0.51) | LMNAMAPTNPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728234-B1 | RADIOLABELED COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2025-05-14 | — | — | EP | claimed |