Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GRK2 | P25098 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139938 | 1.00 | SSTR5 (0.46) | SSTR5KMT2AGRK2CTDSP1L3MBTL1 | |
| SCHEMBL2250087 | 0.86 | KMT2A (0.56) | SSTR5KMT2AGRK2CTDSP1L3MBTL1 | |
| SCHEMBL2250089 | 0.86 | KMT2A (0.56) | SSTR5KMT2AGRK2CTDSP1L3MBTL1 | |
| SCHEMBL3155412 | 0.86 | KMT2A (0.56) | SSTR5KMT2AGRK2CTDSP1L3MBTL1 | |
| SCHEMBL3155227 | 0.81 | SSTR5 (0.46) | SSTR5KMT2AGRK2CTDSP1L3MBTL1 | |
| SCHEMBL3155229 | 0.81 | SSTR5 (0.46) | SSTR5KMT2AGRK2CTDSP1L3MBTL1 | |
| SCHEMBL2255261 | 0.80 | ALDH1A1 (0.47) | SSTR5KMT2AGRK2CTDSP1L3MBTL1 | |
| SCHEMBL2255259 | 0.80 | ALDH1A1 (0.47) | SSTR5KMT2AGRK2CTDSP1L3MBTL1 | |
| SCHEMBL2254545 | 0.77 | SSTR5 (0.44) | SSTR5KMT2AGRK2CTDSP1POLB | |
| SCHEMBL2255568 | 0.73 | SSTR5 (0.49) | SSTR5KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066678-B1 | SPIRO ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-02-10 | — | — | EP | claimed |