SCHEMBL3150893

SCHEMBL3150893

Nc1nc(C2O[C@H](C(O)OP(=O)(O)O)[C@@H](O)[C@@H]2O)nc2nc[nH]c12

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.36
GDA Q9Y2T3 1/20 0.36
KDR P35968 1/20 0.34
AURKB Q96GD4 1/20 0.34
MGMT P16455 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11468514 1.00 PDPK1 (0.36) PDPK1GDAKDRAURKBMGMT
SCHEMBL11478249 1.00 PDPK1 (0.36) PDPK1GDAKDRAURKBMGMT
Phosphoric Acid SCHEMBL1130273 0.77 PDPK1 (0.39) PDPK1GDAKDRAURKB
SCHEMBL11875859 0.75
SCHEMBL8102858 0.73 ADORA1 (0.43) PDPK1GDAKDRAURKB
SCHEMBL9393271 0.72 PDPK1 (0.43) PDPK1GDAKDRAURKB
SCHEMBL240029 0.72 PDPK1 (0.43) PDPK1GDAKDRAURKB
SCHEMBL4436406 0.72 PDPK1 (0.43) PDPK1GDAKDRAURKB
SCHEMBL2636634 0.72 PDPK1 (0.43) PDPK1GDAKDRAURKB
SCHEMBL2010793 0.72 PDPK1 (0.43) PDPK1GDAKDRAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0852499-B1 THERAPEUTIC AZIDE COMPOUNDS UNIV GEORGIA RES FOUND (US) 2010-03-03 EP disclosed
US-6949521-B2 Therapeutic azide compounds THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2005-09-27 US disclosed
US-20010036930-A1 Therapeutic azide compounds UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2001-11-01 US disclosed
US-6271212-B1 MIXTURE WITH CARRIER UNIVERSITY OF GEORGIA RESEARCH FOUNDATION INC. 2001-08-07 US disclosed
EP-0624098-B1 PROCESS OF CONJUGATION OF ANTIVIRAL NUCLEOSIDES WITH LACTOSAMINATED HUMAN ALBUMIN BALDACCI LAB SPA (IT) 2000-03-15 EP disclosed
EP-0852499-A1 THERAPEUTIC AZIDE COMPOUNDS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1998-07-15 EP disclosed
WO-1997009052-A1 THERAPEUTIC AZIDE COMPOUNDS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1997-03-13 WO disclosed
US-5594110-A REACTION OF NUCLEOSIDE IN THE FORM OF AN IMIDAZOLIDE AT A PH ABOVE 7.5 LABORATORI BALDACCI SPA (IT) 1997-01-14 US disclosed
EP-0624098-A1 PROCESS OF CONJUGATION OF ANTIVIRAL NUCLEOSIDES WITH LACTOSAMINATED HUMAN ALBUMIN LABORATORI BALDACCI Spa (IT) 1994-11-17 EP disclosed
WO-1994012218-A1 PROCESS OF CONJUGATION OF ANTIVIRAL NUCLEOSIDES WITH LACTOSAMINATED HUMAN ALBUMIN LABORATORI BALDACCI S.P.A. (IT) 1994-06-09 WO disclosed
EP-0103783-A2 Dermatological preparation Dr. Thilo & Co. GmbH (DE) 1984-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010036930-A1 Therapeutic azide compounds ADA, ADK, DCK PDPK1 409/4885GDA 186/4885KDR 1449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.