SCHEMBL315097

SCHEMBL315097

O=C(O)c1ccc(C(F)F)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.60
TP53 P04637 1/20 0.60
SRD5A2 P31213 4/20 0.52
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
ANPEP P15144 1/20 0.50
CA12 O43570 1/20 0.50
CA3 P07451 1/20 0.50
TYR P14679 1/20 0.50
DRD1 P21728 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
BCL2L1 Q07817 1/20 0.48
BAD Q92934 1/20 0.48
ALDH1A1 P00352 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22468969 0.93 BCL2L1 (0.59) TSHRTP53SRD5A2CA1CA2
SCHEMBL26114408 0.88 SRD5A2 (0.64) TSHRTP53SRD5A2CA1CA2
SCHEMBL6756209 0.85 TSHR (0.60) TSHRTP53SRD5A2CA1CA2
SCHEMBL28608879 0.82 ALDH1A1 (0.48) TSHRTP53SRD5A2ALDH1A1SMN1; SMN2
SCHEMBL4853588 0.81 TSHR (0.55) TSHRTP53SRD5A2CA1CA2
SCHEMBL14488137 0.81 ANPEP (0.57) TSHRTP53SRD5A2CA1CA2
SCHEMBL5211118 0.81 TSHR (0.55) TSHRTP53SRD5A2CA1CA2
SCHEMBL5415219 0.81 TSHR (0.55) TSHRTP53SRD5A2CA1CA2
SCHEMBL8163188 0.80 MRGPRX4 (0.37) TSHRTP53ANPEPALDH1A1SMN1; SMN2
SCHEMBL30378525 0.79 MRGPRX4 (0.41) TSHRTP53SRD5A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116950651-A Tracer agent for oilfield fracturing construction and preparation method thereof 浙江神耀石化科技有限公司 2023-10-27 CN claimed
CN-112851501-A Chemical tracer for fracturing and preparation method and application thereof 中国石油大学(华东) 2021-05-28 CN claimed
EP-3551633-B1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA AS (DK) 2021-03-31 EP claimed
CN-112551522-A Preparation method of silicon-carbon negative electrode material for lithium ion battery 上海纳米技术及应用国家工程研究中心有限公司 2021-03-26 CN claimed
EP-3551633-A1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS Leo Pharma A/S (DK) 2019-10-16 EP claimed
EP-3551634-A1 SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS Leo Pharma A/S (DK) 2019-10-16 EP claimed
CN-110088108-A SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS 利奥制药有限公司 2019-08-02 CN claimed
WO-2018108230-A1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA A/S (DK) 2018-06-21 WO claimed
WO-2018108231-A1 SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA A/S (DK) 2018-06-21 WO claimed
US-9023316-B2 Synthesis of 18F-labeled tracers in hydrous organic solvents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2015-05-05 US claimed
EP-2556372-A1 SYNTHESIS OF 18F-LABELED TRACERS IN HYDROUS ORGANIC SOLVENTS Siemens Medical Solutions USA, Inc. (US) 2013-02-13 EP claimed
US-20130005956-A1 Synthesis of 18F-labeled Tracers in Hydrous Organic Solvents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-01-03 US claimed
WO-2011127345-A1 SYNTHESIS OF 18F-LABELED TRACERS IN HYDROUS ORGANIC SOLVENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2011-10-13 WO claimed
US-20250388604-A1 Compounds and Their Use as PDE4 Activators MIRONID LIMITED (GB) 2025-12-25 US disclosed
US-20250361249-A1 SURFACE TREATMENT AGENT DAIKIN INDUSTRIES, LTD. (JP) 2025-11-27 US disclosed
EP-4644398-A1 SURFACE TREATMENT AGENT Daikin Industries, Ltd. (JP) 2025-11-05 EP disclosed
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 EP disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 WO disclosed
US-4051168-A TO FORM FLUOROALKYL AROMATIC COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130005956-A1 Synthesis of 18F-labeled Tracers in Hydrous Organic Solvents SLCO1B1, SLCO4C1, SLCO2B1 TSHR 3216/4885TP53 2034/4885SRD5A2 1152/4885
US-20250388604-A1 Compounds and Their Use as PDE4 Activators PDE4A, PDE7A, PDE4B TSHR 1206/4885TP53 4753/4885SRD5A2 110/4885
US-20250361249-A1 SURFACE TREATMENT AGENT ITGA1, ITGB1, GDI1 TSHR 395/4885TP53 1057/4885SRD5A2 1541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.