SCHEMBL31510364

SCHEMBL31510364

N=C(N)Nc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.56
▸ POLB P06746 5/20 0.49
▸ ALDH1A1 P00352 1/20 0.49
▸ CYP1A2 P05177 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.49
▸ CYP3A4 P08684 1/20 0.46
▸ KMT2A Q03164 2/20 0.44
▸ GAA P10253 1/20 0.44
▸ MEN1 O00255 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20534511 0.76 LMNA (0.62) LMNAPOLBALDH1A1CYP1A2SMN1; SMN2
SCHEMBL2552963 0.71 CYP3A4 (0.57) LMNAPOLBALDH1A1CYP1A2SMN1; SMN2
SCHEMBL23055551 0.70 LMNA (0.69) LMNAPOLBALDH1A1CYP1A2SMN1; SMN2
SCHEMBL11879018 0.70 ATAD2 (0.52) LMNAPOLBALDH1A1CYP1A2SMN1; SMN2
SCHEMBL31045621 0.69 LMNA (0.54) LMNAPOLBALDH1A1CYP1A2SMN1; SMN2
SCHEMBL31258082 0.69 ALDH1A1 (0.62) LMNAPOLBALDH1A1CYP1A2SMN1; SMN2
SCHEMBL2532353 0.68 LMNA (0.53) LMNAPOLBALDH1A1CYP1A2SMN1; SMN2
SCHEMBL2532356 0.68 LMNA (0.53) LMNAPOLBALDH1A1CYP1A2SMN1; SMN2
SCHEMBL2532358 0.68 LMNA (0.53) LMNAPOLBALDH1A1CYP1A2SMN1; SMN2
SCHEMBL13609115 0.68 LMNA (0.56) LMNAPOLBALDH1A1CYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4644403-A1 HALOGEN-CONTAINING COMPOUNDS USED FOR CAPPING THE 5' END OF NUCLEIC ACID AND USE THEREOF Shenzhen Rhegen Biotechnology Co., Ltd. (CN) 2025-11-05 — — EP disclosed
WO-2025082058-A1 DSRNA THAT INHIBITS EXPRESSION OF LPA GENE AND USE THEREOF 润佳(上海)医药技术有限公司 2025-04-24 — — WO disclosed
WO-2025082057-A1 INHIBITOR FOR INHIBITING EXPRESSION OF INHIBIN BETA E GENE AND USE THEREOF 润佳(上海)医药技术有限公司 2025-04-24 — — WO disclosed
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