Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 5/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | MELK | Q14680 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514556 | 0.92 | FGFR1 (0.49) | TDO2EGFRALKMAP4K4AURKB | |
| SCHEMBL31514594 | 0.90 | AURKB (0.49) | TDO2EGFRALKMAP4K4AURKB | |
| SCHEMBL31514608 | 0.90 | DGAT1 (0.50) | TDO2EGFRMAP4K4AURKB | |
| SCHEMBL31514592 | 0.89 | TDO2 (0.48) | TDO2EGFRMAP4K4NTRK1 | |
| SCHEMBL31514621 | 0.86 | EGFR (0.50) | TDO2EGFRMAP4K4AURKBKIT | |
| SCHEMBL31514563 | 0.85 | EGFR (0.51) | TDO2EGFRMAP4K4AURKBKIT | |
| SCHEMBL31514561 | 0.84 | DGAT1 (0.50) | TDO2EGFRMAP4K4AURKBFGFR1 | |
| SCHEMBL31514586 | 0.83 | EGFR (0.48) | TDO2EGFRMAP4K4AURKBKIT | |
| SCHEMBL31514603 | 0.83 | EGFR (0.47) | EGFRMAP4K4AURKBKITFLT3 | |
| SCHEMBL31514585 | 0.81 | CD38 (0.48) | EGFRALKAURKBKITFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912429-A | Quinazoline compound with anti-inflammatory activity or pharmaceutically acceptable salt thereof, pharmaceutical composition and application thereof | 安徽医科大学 | 2025-05-02 | — | — | CN | disclosed |